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Delivering next-generation cancer therapies targeting cell state

By identifying and targeting the dysregulated cell states of cancer, we aim to transform the treatment of solid tumors and hematological malignancies with the next generation of targeted cancer therapies.

Atlases to Map Cancer Cell States

We have combined a proprietary database of single cell genomic data with an AI-powered computational platform that allows us to compare healthy cell development to cancer cell development and map out the drivers of tumorigenesis.

A Diverse Team of Innovators

We have assembled a team with deep expertise in cancer biology, medicinal chemistry, and computational science who work closely with leading physician-scientists.

Patient
Centered

At the center of everything we do are the patients. As pioneers in cancer cell state drug development, we aim to offer patients longer, higher quality lives.

Our Team

Platform
Powered

Our AI platform, AURIGIN™, allows us to identify targets, model systems, and biomarkers for efficient discovery and development of targeted cancer therapies.

Our Science

Product
Driven

Our pipeline is a direct result of our AURIGIN™ platform. Using AURIGIN, we are advancing programs designed to address the critical unmet needs of patients with solid tumor cancers or hematologic malignancies.

Our Pipeline

An urgent unmet need

The initial indications of our flagship candidate are cancers with high mortality rates.

30,000+ per year

Small-cell lung cancer (SCLC)

SCLC has a poor outlook due to late diagnosis and speed of spread

7%
Overall 5-year survival rate

15,000+ per year

Neuroendocrine prostate cancer (NEPC)

NEPC has a poor outlook due to late diagnosis and lack of effective treatment.

14%
Overall 5-year survival rate

20,000+ per year

Acute Myeloid Leukemia (AML)

AML has a poor outlook due to late diagnosis and speed of spread

30%
Overall 5-year survival rate
SOURCES:
  1. US population incidence rates from American Cancer Society (2023)
  2. Cancer.org — Source
  3. Over 288K new cases of prostate cancer (PC) per year (Source - Cancer.org) and 0.5% to 2% of newly diagnosed PC are classified as NEPC (Source - NCBI)
  4. NCBI — Source
  5. Leukemia & Lymphoma Society — Source
  6. Leukemia & Lymphoma Society — Source

Focused Team.
One purpose.

We have fostered a culture that encourages our team to be curious, to think strategically and creatively, and to push the limits of science. We honor diversity and individuality, and are united by a single commitment to serve the patients and families who need new treatments.

Make an impact.

Search for open positions at Auron Therapeutics.

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Recent News

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August 19, 2024

Auron Presents Preclinical Data at American Chemical Society Annual Meeting

Newton, MA, August 19, 2024 – Auron Therapeutics, a biotechnology company focused on developing next-generation targeted therapies by identifying and inhibiting the oncogenic cell states of cancer, today shared preclinical data showcasing the strength of the company’s medicinal chemistry capabilities. These discovery research data, presented at the American Chemical Society (ACS) Annual Meeting, are from the company’s lead program targeting KAT2A/B, a histone acetyltransferase driving multiple cancer types.

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